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Human Papillomavirus (HPV) infections are caused by Human papillomavirus and spread through sexual activity and direct contact. It is one of the most common sexually transmitted infections (STIs) and causes skin or mucous membrane overgrowths called warts. More than 100 varieties of human papillomavirus (HPV) have been identified. Some types cause common warts that can grow in any body part, particularly hands, fingers, plantar region of feet, etc. Some HPV can cause different cancers, especially HPV 16 and HPV 18. All HPV infections don't result in cancer, but genital HPV can cause cancer of the cervix. Other HPV types can cause different types of cancers, including cancers of the anus, penis, vagina, vulva, and oropharynx. Vaccines are helpful against some HPV, especially those that cause genital warts or cervical cancer.